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The Enzymatic Release of O(6)-methylguanine and 3-methyladenine from DNA Reacted with the Carcinogen N-methyl-N-nitrosourea
Endonuclease II (deoxyribonucleate oligonucleotidohydrolase, EC 3.1.4.30) of Escherichia coli has been shown to break phosphodiester bonds in alkylated DNA and depurinated DNA. The hypothesis that depurination is a step in the mechanism of the reaction with alkylated DNA is supported by in vitro exp...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1974
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388377/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4600266/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.5.2022 |
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