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The great escape: Active genes on inactive sex chromosomes and their evolutionary implications

Epigenetic mechanisms precisely regulate sex chromosome inactivation as well as genes that escape the silencing process. In male germ cells, DNA damage response factor RNF8 establishes active epigenetic modifications on the silent sex chromosomes during meiosis, and activates escape genes during a s...

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Bibliografiske detaljer
Main Authors: Sin, Ho-Su, Namekawa, Satoshi H
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883765/
https://ncbi.nlm.nih.gov/pubmed/23880818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.25672
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