HIV-1/Cocaine Induced Oxidative Stress Disrupts Tight Junction Protein-1 in Human Pulmonary Microvascular Endothelial Cells: Role of Ras/ERK1/2 Pathway

Intravenous drug use (IVDU) is the major risk factor in the development of HIV-related pulmonary arterial hypertension (HRPAH); however, the pathogenesis of HRPAH in association with IVDU has yet to be characterized. Endothelial injury is considered to be an initiating factor for pulmonary vascular...

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Detalhes bibliográficos
Main Authors: Dalvi, Pranjali, Wang, Kun, Mermis, Joel, Zeng, Ruoxi, Sanderson, Miles, Johnson, Sara, Dai, Yuqiao, Sharma, Garima, Ladner, Amy O’Brien, Dhillon, Navneet K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883699/
https://ncbi.nlm.nih.gov/pubmed/24409324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085246
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