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Pathway-GPS and SIGORA: identifying relevant pathways based on the over-representation of their gene-pair signatures
Motivation. Predominant pathway analysis approaches treat pathways as collections of individual genes and consider all pathway members as equally informative. As a result, at times spurious and misleading pathways are inappropriately identified as statistically significant, solely due to components...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
PeerJ Inc.
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3883547/ https://ncbi.nlm.nih.gov/pubmed/24432194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.229 |
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