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An antibody-interleukin 2 fusion protein overcomes tumor heterogeneity by induction of a cellular immune response.

Antibody-based therapies for cancer rely on the expression of defined antigens on neoplastic cells. However, most tumors display heterogeneity in the expression of such antigens. We demonstrate here that antibody-targeted interleukin 2 delivery overcomes this problem by induction of a host immune re...

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Bibliografische gegevens
Hoofdauteurs: Becker, J C, Varki, N, Gillies, S D, Furukawa, K, Reisfeld, R A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1996
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC38833/
https://ncbi.nlm.nih.gov/pubmed/8755561
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