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A new method to detect rapid oxygen changes around cells: How quickly do calcium channels sense oxygen in cardiomyocytes?

Acute hypoxia is thought to trigger protective responses that, in tissues like heart and carotid body, include rapid (5–10 s) suppression of Ca(2+) and K(+) channels. To gain insight into the mechanism for the suppression of the cardiac l-type Ca(2+) channel, we measured O(2)-dependent fluorescence...

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Главные авторы: Scaringi, John A., Rosa, Angelo Oscar, Morad, Martin, Cleemann, Lars
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882939/
https://ncbi.nlm.nih.gov/pubmed/24157525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00770.2013
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