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L-type calcium channel as a cardiac oxygen sensor
Acute oxygen sensing in the heart is thought to occur through redox regulation and phosphorylation of membrane channels. Here we report a novel O(2)-sensing mechanism involving the C-terminus of the L-type Ca(2+) channel and regulated by PKA phosphorylation. In patch-clamped myocytes, oxygen depriva...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3064564/ https://ncbi.nlm.nih.gov/pubmed/20201898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2009.05095.x |
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