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Dbl3 drives Cdc42 signaling at the apical margin to regulate junction position and apical differentiation

Epithelial cells develop morphologically characteristic apical domains that are bordered by tight junctions, the apical–lateral border. Cdc42 and its effector complex Par6–atypical protein kinase c (aPKC) regulate multiple steps during epithelial differentiation, but the mechanisms that mediate proc...

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Autori principali: Zihni, Ceniz, Munro, Peter M.G., Elbediwy, Ahmed, Keep, Nicholas H., Terry, Stephen J., Harris, John, Balda, Maria S., Matter, Karl
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882792/
https://ncbi.nlm.nih.gov/pubmed/24379416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201304064
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