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Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex

Epithelial cell–cell adhesion and morphogenesis require dynamic control of actin-driven membrane remodeling. The Rho guanosine triphosphatase (GTPase) Cdc42 regulates sequential molecular processes during cell–cell junction formation; hence, mechanisms must exist that inactivate Cdc42 in a temporall...

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Detalhes bibliográficos
Main Authors: Elbediwy, Ahmed, Zihni, Ceniz, Terry, Stephen J., Clark, Peter, Matter, Karl, Balda, Maria S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514035/
https://ncbi.nlm.nih.gov/pubmed/22891260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201202094
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