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Insulin resistance protects the heart from fuel overload in dysregulated metabolic states

Reversing impaired insulin sensitivity has been suggested as treatment for heart failure. However, recent clinical evidence suggests the opposite. Here we present a line of reasoning in support of the hypothesis that insulin resistance protects the heart from the consequences of fuel overload in the...

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Main Authors: Taegtmeyer, Heinrich, Beauloye, Christophe, Harmancey, Romain, Hue, Louis
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882545/
https://ncbi.nlm.nih.gov/pubmed/24097426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00854.2012
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