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Estradiol activates epithelial sodium channels in rat alveolar cells through the G protein-coupled estrogen receptor

Female sex predisposes individuals to poorer outcomes during respiratory disorders like cystic fibrosis and influenza-associated pneumonia. A common link between these disorders is dysregulation of alveolar fluid clearance via disruption of epithelial sodium channel (ENaC) activity. Recent evidence...

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Detalhes bibliográficos
Main Authors: Greenlee, Megan M., Mitzelfelt, Jeremiah D., Yu, Ling, Yue, Qiang, Duke, Billie Jeanne, Harrell, Constance S., Neigh, Gretchen N., Eaton, Douglas C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882529/
https://ncbi.nlm.nih.gov/pubmed/24097558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00008.2013
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