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Metformin-stimulated AMPK-α1 promotes microvascular repair in acute lung injury
Acute lung injury secondary to sepsis is a leading cause of mortality in sepsis-related death. Present therapies are not effective in reversing endothelial cell dysfunction, which plays a key role in increased vascular permeability and compromised lung function. AMP-activated protein kinase (AMPK) i...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Physiological Society
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3882528/ https://ncbi.nlm.nih.gov/pubmed/24097562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00173.2013 |
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