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Extracellular Allosteric Na(+) Binding to the Na(+),K(+)-ATPase in Cardiac Myocytes

Whole-cell patch-clamp measurements of the current, I(p), produced by the Na(+),K(+)-ATPase across the plasma membrane of rabbit cardiac myocytes show an increase in I(p) over the extracellular Na(+) concentration range 0–50 mM. This is not predicted by the classical Albers-Post scheme of the Na(+),...

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Autori principali: Garcia, Alvaro, Fry, Natasha A.S., Karimi, Keyvan, Liu, Chia-chi, Apell, Hans-Jürgen, Rasmussen, Helge H., Clarke, Ronald J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882478/
https://ncbi.nlm.nih.gov/pubmed/24359741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.11.004
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