Reduced hepatic mitochondrial respiration following acute high-fat diet is prevented by PGC-1α overexpression

Changes in substrate utilization and reduced mitochondrial respiratory capacity following exposure to energy-dense, high-fat diets (HFD) are putatively key components in the development of obesity-related metabolic disease. We examined the effect of a 3-day HFD on isolated liver mitochondrial respir...

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Detalhes bibliográficos
Main Authors: Morris, E. Matthew, Jackman, Matthew R., Meers, Grace M. E., Johnson, Ginger C., Lopez, Jordan L., MacLean, Paul S., Thyfault, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Liver and Biliary Tract
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882433/
https://ncbi.nlm.nih.gov/pubmed/24091599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00179.2013
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