Mechanisms of STAT3 activation in the liver of FXR knockout mice

Farnesoid X receptor (FXR, Nr1h4) is a ligand-activated transcription factor belonging to the nuclear receptor superfamily. FXR is essential in maintaining bile acid (BA) homeostasis, and FXR(−/−) mice develop cholestasis, inflammation, and spontaneous liver tumors. The signal transducer and activat...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Li, Guodong, Zhu, Yan, Tawfik, Ossama, Kong, Bo, Williams, Jessica A., Zhan, Le, Kassel, Karen M., Luyendyk, James P., Wang, Li, Guo, Grace L.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2013
Sujets:
Liver and Biliary Tract
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882431/
https://ncbi.nlm.nih.gov/pubmed/24091600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00155.2013
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