The Three Dimensional Structure of a Combining Region-Ligand Complex of Immunoglobulin NEW at 3.5-Å Resolution

IgG New binds ligands such as orceine, menadione, and uridine with a low affinity (K(0) about 1 × 10(3) liter/mol) and a γ-hydroxy derivative of vitamin K(1) with a higher affinity (K(0) = 1.7 × 10(5) liter/mol). Binding studies indicate that both the 2-methylnaphthoquinone rings and the phytyl tail...

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發表在:	Proc Natl Acad Sci U S A
Principais autores:	Amzel, L. M., Poljak, R. J., Saul, F., Varga, J. M., Richards, Frank F.
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 1974
主題:	Biological Sciences: Immunology
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388242/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4524646/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.4.1427
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