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Crystals of Phosphorylcholine-Binding Fab-Fragments from Mouse Myeloma Proteins: Preparation and X-Ray Analysis

Fab-fragments of several phosphorylcholine-binding mouse-myeloma proteins have been prepared by pepsin digestion; two of these, MOPC 167 and McPC 603, gave large crystals from ammonium sulfate solutions. The Fab-fragment from MOPC 167 crystallizes in a hexagonal space group, but does not diffract to...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Rudikoff, Stuart, Potter, Michael, Segal, David M., Padlan, Eduardo A., Davies, David R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1972
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389850/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4566456/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.12.3689
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