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Exploiting the Synergy between Carboplatin and ABT-737 in the Treatment of Ovarian Carcinomas
Platinum drug-resistance in ovarian cancers mediated by anti-apoptotic proteins such as Bcl-xL is a major factor contributing to the chemotherapeutic resistance of recurrent disease. Consequently, concurrent inhibition of Bcl-xL in combination with chemotherapy may improve treatment outcomes for pat...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3882219/ https://ncbi.nlm.nih.gov/pubmed/24400068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081582 |
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