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Rescuing Recombinant Proteins by Sequestration Into the P22 VLP

Here we report the use of a self-assembling protein cage to sequester and solubilize recombinant proteins which are usually trafficked to insoluble inclusion bodies. Our results suggest that protein cages can be used as novel vehicles to rescue and produce soluble proteins that are otherwise difficu...

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Autors principals: Patterson, Dustin P., LaFrance, Benjamin, Douglas, Trevor
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882142/
https://ncbi.nlm.nih.gov/pubmed/24079011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc46517a
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