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Rescuing Recombinant Proteins by Sequestration Into the P22 VLP

Here we report the use of a self-assembling protein cage to sequester and solubilize recombinant proteins which are usually trafficked to insoluble inclusion bodies. Our results suggest that protein cages can be used as novel vehicles to rescue and produce soluble proteins that are otherwise difficu...

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Detalhes bibliográficos
Main Authors: Patterson, Dustin P., LaFrance, Benjamin, Douglas, Trevor
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882142/
https://ncbi.nlm.nih.gov/pubmed/24079011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc46517a
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