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Rescuing Recombinant Proteins by Sequestration Into the P22 VLP

Here we report the use of a self-assembling protein cage to sequester and solubilize recombinant proteins which are usually trafficked to insoluble inclusion bodies. Our results suggest that protein cages can be used as novel vehicles to rescue and produce soluble proteins that are otherwise difficu...

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Main Authors: Patterson, Dustin P., LaFrance, Benjamin, Douglas, Trevor
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882142/
https://ncbi.nlm.nih.gov/pubmed/24079011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc46517a
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