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TL1A and DR3, a TNF-family ligand-receptor pair that promotes lymphocyte costimulation, mucosal hyperplasia and autoimmune inflammation

DR3 (TNFRSF25) is a member of the tumor necrosis factor receptor (TNFR) superfamily expressed primarily on lymphocytes and is a receptor for the TNF family cytokine TL1A (TNFSF15). DR3 costimulates T cell activation, but it is unique among these receptors in that it signals through an intracytoplasm...

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Detalhes bibliográficos
Main Authors: Meylan, Françoise, Richard, Arianne C., Siegel, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882070/
https://ncbi.nlm.nih.gov/pubmed/22017439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2011.01068.x
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