Dysregulated phosphatidylinositol signaling promotes endoplasmic-reticulum-stress-mediated intestinal mucosal injury and inflammation in zebrafish

Dysregulated phosphatidylinositol (PI) signaling has been implicated in human gastrointestinal (GI) malignancies and inflammatory states, underlining the need to study pathophysiological roles of PI in an in vivo genetic model. Here, we study the significance of PI in GI pathophysiology using the ze...

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Hlavní autoři: Thakur, Prakash C., Davison, Jon M., Stuckenholz, Carsten, Lu, Lili, Bahary, Nathan
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Limited 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882052/
https://ncbi.nlm.nih.gov/pubmed/24135483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.012864
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