Lack of de novo Phosphatidylinositol Synthesis Leads to Endoplasmic Reticulum Stress and Hepatic Steatosis in cdipt-Deficient Zebrafish

Hepatic steatosis is the initial stage of non-alcoholic fatty liver disease (NAFLD) and may predispose to more severe hepatic disease, including hepatocellular carcinoma. Endoplasmic reticulum (ER) stress has been recently implicated as a novel mechanism that may lead to NAFLD, although the genetic...

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Hlavní autoři: Thakur, Prakash C, Stuckenholz, Carsten, Rivera, Marcus R, Davison, Jon M, Yao, Jeffrey K, Amsterdam, Adam, Sadler, Kirsten C, Bahary, Nathan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140628/
https://ncbi.nlm.nih.gov/pubmed/21488074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24349
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