A Hyperglycemic Peptide from Pituitary Growth Hormone: Preparation with Pepsin and Assay in ob/ob Mice
A fragment that induces glucose intolerance in hereditarily obese mice has been prepared from pituitary growth hormone(sheep and human) by controlled digestion with pepsin in 0.05 M sodium acetate buffer, pH 3.7. The digest was purified by column chromatography on Bio-Gel P-6, followed by chromatogr...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1974
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388201/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4598296/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.4.1244 |
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