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A Hyperglycemic Peptide from Pituitary Growth Hormone: Preparation with Pepsin and Assay in ob/ob Mice

A fragment that induces glucose intolerance in hereditarily obese mice has been prepared from pituitary growth hormone(sheep and human) by controlled digestion with pepsin in 0.05 M sodium acetate buffer, pH 3.7. The digest was purified by column chromatography on Bio-Gel P-6, followed by chromatogr...

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Detalhes bibliográficos
Main Authors: Lostroh, Ardis J., Krahl, M. E.
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC388201/
https://ncbi.nlm.nih.gov/pubmed/4598296
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