Isolation of a Clone of Chinese Hamster Ovary Cells Deficient in Plant Lectin-Binding Sites
Ricin, a galactose-binding lectin with potent cytotoxic activity, was used to select a clone of Chinese hamster ovary cells with altered plant lectin-binding properties. The clone (15B) is 80-fold less sensitive to the toxic action of ricin than the parent line. In the absence of ricin, it grows bot...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1974
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388166/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4524616/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.4.1078 |
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