Isolation of a Clone of Chinese Hamster Ovary Cells Deficient in Plant Lectin-Binding Sites

Ricin, a galactose-binding lectin with potent cytotoxic activity, was used to select a clone of Chinese hamster ovary cells with altered plant lectin-binding properties. The clone (15B) is 80-fold less sensitive to the toxic action of ricin than the parent line. In the absence of ricin, it grows bot...

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發表在:	Proc Natl Acad Sci U S A
Principais autores:	Gottlieb, Charlene, Skinner, Sister Ann Marie, Kornfeld, Stuart
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 1974
主題:	Biological Sciences: Biochemistry
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388166/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4524616/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.4.1078
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