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Application of diazene-directed fragment assembly to the total synthesis and stereochemical assignment of (+)-desmethyl-meso-chimonanthine and related heterodimeric alkaloids

We describe the first application of our methodology for heterodimerization via diazene fragmentation towards the total synthesis of (−)-calycanthidine, meso-chimonanthine, and (+)-desmethyl-meso-chimonanthine. Our syntheses of these alkaloids feature an improved route to C3a-aminocyclotryptamines,...

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Detalhes bibliográficos
Main Authors: Lathrop, Stephen P., Movassaghi, Mohammad
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3881597/
https://ncbi.nlm.nih.gov/pubmed/24409339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3SC52451E
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