TIMP-2 mutant decreases MMP-2 activity and augments pressure overload induced LV dysfunction and heart failure

Pressure overload induces cardiac extracellular matrix (ECM) remodelling and results in heart failure. ECM remodelling by matrix metalloproteinases (MMPs) is primarily regulated by their target inhibitors, tissue inhibitor of matrix metalloproteinases (TIMPs). It is known that TIMP-2 is highly expre...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Givvimani, S., Kundu, S., Narayanan, N., Armaghan, F., Qipshidze, N., Pushpakumar, S., Vacek, T. P., Tyagi, S. C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3881363/
https://ncbi.nlm.nih.gov/pubmed/23398532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/13813455.2012.755548
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы