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Emergence of anxiety-like behaviors in depressive-like Cpe(fat/fat) mice
Cpe(fat/fat) mice have a point mutation in carboxypeptidase E (CPE), an exopeptidase that removes C-terminal basic amino acids from intermediates to produce bioactive peptides. The mutation renders the enzyme inactive and unstable. The absence of CPE activity in these mutants leads to abnormal proce...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3881283/ https://ncbi.nlm.nih.gov/pubmed/23442571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S1461145713000059 |
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