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Serotonin-Sensitive Adenylate Cyclase in Neural Tissue and Its Similarity to the Serotonin Receptor: A Possible Site of Action of Lysergic Acid Diethylamide

An adenylate cyclase (EC 4.6.1.1) that is activated specifically by low concentrations of serotonin has been identified in homogenates of the thoracic ganglia of an insect nervous system. The activation of this enzyme by serotonin was selectively inhibited by extremely low concentrations of D-lyserg...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Nathanson, James A., Greengard, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1974
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388101/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4595572/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.3.797
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