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Myotonic dystrophy mouse models: towards rational therapy development
DNA repeat expansions can result in the production of toxic RNA. RNA toxicity has been best characterised in the context of myotonic dystrophy. Nearly 20 mouse models have contributed significant and complementary insights into specific aspects of this novel disease mechanism. These models provide a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3881009/ https://ncbi.nlm.nih.gov/pubmed/21724467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2011.05.004 |
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