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Behavioral and transcriptome alterations in male and female mice with postnatal deletion of TrkB in dorsal striatal medium spiny neurons

BACKGROUND: The high affinity tyrosine kinase receptor, TrkB, is the primary receptor for brain derived neurotrophic factor (BDNF) and plays an important role in development, maintenance and plasticity of the striatal output medium size spiny neuron. The striatal BDNF/TrkB system is thereby implicat...

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Bibliografiske detaljer
Main Authors: Unterwald, Ellen M, Page, Michelle E, Brown, Timothy B, Miller, Jonathan S, Ruiz, Marta, Pescatore, Karen A, Xu, Baoji, Reichardt, Louis French, Beverley, Joel, Tang, Bin, Steiner, Heinz, Thomas, Elizabeth A, Ehrlich, Michelle E
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880973/
https://ncbi.nlm.nih.gov/pubmed/24369067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-8-47
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