Behavioral and transcriptome alterations in male and female mice with postnatal deletion of TrkB in dorsal striatal medium spiny neurons

BACKGROUND: The high affinity tyrosine kinase receptor, TrkB, is the primary receptor for brain derived neurotrophic factor (BDNF) and plays an important role in development, maintenance and plasticity of the striatal output medium size spiny neuron. The striatal BDNF/TrkB system is thereby implicat...

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Main Authors: Unterwald, Ellen M, Page, Michelle E, Brown, Timothy B, Miller, Jonathan S, Ruiz, Marta, Pescatore, Karen A, Xu, Baoji, Reichardt, Louis French, Beverley, Joel, Tang, Bin, Steiner, Heinz, Thomas, Elizabeth A, Ehrlich, Michelle E
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880973/
https://ncbi.nlm.nih.gov/pubmed/24369067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-8-47
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