BAG-1 suppresses expression of the key regulatory cytokine transforming growth factor beta [TGF-β1] in colorectal tumour cells

As colorectal cancer remains the second highest cause of cancer-related deaths in much of the industrialised world, identifying novel strategies to prevent colorectal tumour development remains an important challenge. BAG-1 is a multi-functional protein, the expression of which is up-regulated at re...

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Huvudupphovsmän: Skeen, Victoria R., Collard, Tracey J., Southern, Samantha L., Greenhough, Alexander, Hague, Angela, Townsend, Paul, Paraskeva, Christos, Williams, Ann C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880928/
https://ncbi.nlm.nih.gov/pubmed/23108401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.480
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