The TCR γδ Repertoire and Relative Gene Expression Characteristics of T-ALL Cases with Biclonal Malignant Vδ1 and Vδ2 T Cells

Despite significant improvement in our understanding of T-cell acute lymphoblastic leukemia (T-ALL) biology and pathogenesis, many questions remain unanswered. In previous studies, we found a T-ALL case with two malignant T-cell clones with Vδ1Dδ2Dδ3Jδ1 and Vδ2Dδ3Jδ2 rearrangements. In this study, w...

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Detalhes bibliográficos
Main Authors: Zheng, Haitao, Wang, Xu, Ma, Yu, Xu, Bing, Chen, Shaohua, Yang, Lijian, Wu, Xiuli, Przybylski, Grzegorz K., Huang, Suming, Ye, Tiezhen, Li, Yangqiu
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Inflammation & Host Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880916/
https://ncbi.nlm.nih.gov/pubmed/24329526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2013.2199
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