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Interaction between NO synthase and NADPH oxidase in control of sodium transport by the renal thick ascending limb during diabetes

AIM: During type 1 diabetes (T1D), the medullary thick ascending limb (mTAL) displays an NADPH oxidase-dependent increase in sodium transport, in concert with increased NO production by NO synthase 1 (NOS1) and NOS2. We hypothesized that NOS1- and/or NOS2-derived NO blunts T1D-induced activation of...

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Bibliografiske detaljer
Main Authors: De Miguel, Carmen, Foster, Jan M., Carmines, Pamela K., Pollock, Jennifer S.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880686/
https://ncbi.nlm.nih.gov/pubmed/23841645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apha.12144
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