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Hepatic oxidative stress activates the Gadd45b gene via degradation of the transcriptional repressor STAT3

Growth arrest and DNA damage-inducible beta (GADD45b) plays an important role in many intracellular events, such as cell cycle arrest, DNA repair, cell survival, apoptosis and senescence. However, its mechanism of transcriptional regulation remains unclear. In this study, the mechanism of proliferat...

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Detalhes bibliográficos
Main Authors: Kim, Jung-Hwan, Qu, Aijuan, Reddy, Janardan K., Gao, Bin, Gonzalez, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880633/
https://ncbi.nlm.nih.gov/pubmed/23939942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26683
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