Distinct Cyclosporin A Doses Are Required to Enhance Bone Formation Induced by Cyclic and Rest-Inserted Loading in the Senescent Skeleton

Age-related decline in periosteal adaptation negatively impacts the ability to utilize exercise to enhance bone mass and strength in the elderly. We recently observed that in senescent animals subject to cyclically applied loading, supplementation with Cyclosporin A (CsA) substantially enhanced the...

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Main Authors: Srinivasan, Sundar, Threet, Dewayne, Worton, Leah E., Ausk, Brandon J., Bain, Steven D., Gardiner, Edith M., Kwon, Ronald Y., Gross, Ted S.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880323/
https://ncbi.nlm.nih.gov/pubmed/24404194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084868
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