STAT3 Oligonucleotide Inhibits Tumor Angiogenesis in Preclinical Models of Squamous Cell Carcinoma

PURPOSE: Signal transducer and activator of transcription 3 (STAT3) has shown to play a critical role in head and neck squamous cell carcinoma (HNSCC) and we have recently completed clinical trials of STAT3 decoy oligonucleotide in patients with recurrent or metastatic HNSCC. However, there is limit...

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Main Authors: Klein, Jonah D., Sano, Daisuke, Sen, Malabika, Myers, Jeffrey N., Grandis, Jennifer R., Kim, Seungwon
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880270/
https://ncbi.nlm.nih.gov/pubmed/24404126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081819
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