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STAT3 Oligonucleotide Inhibits Tumor Angiogenesis in Preclinical Models of Squamous Cell Carcinoma

PURPOSE: Signal transducer and activator of transcription 3 (STAT3) has shown to play a critical role in head and neck squamous cell carcinoma (HNSCC) and we have recently completed clinical trials of STAT3 decoy oligonucleotide in patients with recurrent or metastatic HNSCC. However, there is limit...

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Detalhes bibliográficos
Main Authors: Klein, Jonah D., Sano, Daisuke, Sen, Malabika, Myers, Jeffrey N., Grandis, Jennifer R., Kim, Seungwon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880270/
https://ncbi.nlm.nih.gov/pubmed/24404126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081819
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