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Discovery of a cAMP Deaminase That Quenches Cyclic AMP-Dependent Regulation

An enzyme of unknown function within the amidohydrolase superfamily was discovered to catalyze the hydrolysis of the universal second messenger, cyclic-3’, 5’-adenosine monophosphate (cAMP). The enzyme, which we have named CadD, is encoded by the human pathogenic bacterium Leptospira interrogans. Al...

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Autors principals: Goble, Alissa M., Feng, Youjun, Raushel, Frank M., Cronan, John E.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880142/
https://ncbi.nlm.nih.gov/pubmed/24074367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb4004628
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