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Investigating the role of substrate stiffness in the persistence of valvular interstitial cell activation
During heart valve remodeling and in many disease states, valvular interstitial cells (VICs) shift to an activated myofibroblast phenotype characterized by enhanced synthetic and contractile activity. Pronounced alpha smooth muscle actin (αSMA)-positive stress fibers, the hallmark of activated myofi...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3880130/ https://ncbi.nlm.nih.gov/pubmed/22581728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.34162 |
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