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Physiological consequences of complex II inhibition for aging, disease, and the mK(ATP) channel

In recent years, it has become apparent that there exist several roles for respiratory complex II beyond metabolism. These include: (i) succinate signaling, (ii) reactive oxygen species (ROS) generation, (iii) ischemic preconditioning, (iv) various disease states and aging, (v) a role in the functio...

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Detalhes bibliográficos
Main Authors: Wojtovich, Andrew P., Smith, C. Owen, Haynes, Cole M., Nehrke, Keith W., Brookes, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880126/
https://ncbi.nlm.nih.gov/pubmed/23291191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2012.12.007
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