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The complex II inhibitor atpenin A5 protects against cardiac ischemia-reperfusion injury via activation of mitochondrial K(ATP) channels

The cardioprotective effects of ischemic preconditioning (IPC) can be mimicked or blocked by pharmacologic agents which modulate the mitochondrial ATP-sensitive potassium (mK(ATP)) channel, thereby implicating this channel in the mechanism of IPC. Cardioprotection can also be achieved via inhibition...

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Bibliografske podrobnosti
Main Authors: Wojtovich, Andrew P., Brookes, Paul S.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776710/
https://ncbi.nlm.nih.gov/pubmed/19242645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-009-0001-y
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