Activation of RAC-protein kinase by heat shock and hyperosmolarity stress through a pathway independent of phosphatidylinositol 3-kinase.

RAC protein kinase (RAC-PK), a serine/threonine protein kinase containing a pleckstrin homology (PH) domain, was activated by cellular stress such as heat shock and hyperosmolarity. Wortmannin, which is known as a potent inhibitor of phosphatidylinositol 3-kinase and normally inhibits growth factor-...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Konishi, H, Matsuzaki, H, Tanaka, M, Ono, Y, Tokunaga, C, Kuroda, S, Kikkawa, U
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38799/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8755528/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.15.7639
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