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Activation of RAC-protein kinase by heat shock and hyperosmolarity stress through a pathway independent of phosphatidylinositol 3-kinase.

RAC protein kinase (RAC-PK), a serine/threonine protein kinase containing a pleckstrin homology (PH) domain, was activated by cellular stress such as heat shock and hyperosmolarity. Wortmannin, which is known as a potent inhibitor of phosphatidylinositol 3-kinase and normally inhibits growth factor-...

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Detalhes bibliográficos
Main Authors: Konishi, H, Matsuzaki, H, Tanaka, M, Ono, Y, Tokunaga, C, Kuroda, S, Kikkawa, U
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC38799/
https://ncbi.nlm.nih.gov/pubmed/8755528
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