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T-Cell Factor/β-Catenin Activity is Suppressed Normally in Two Independent Models of Autosomal Dominant Polycystic Kidney Disease

During murine kidney development, canonical WNT signalling is highly active in the renal tubules until about embryonic day E16-E18 when β-catenin transcriptional activity becomes progressively restricted to the nephrogenic zone. Several in vitro studies have found a link between cilial signalling an...

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Bibliografiske detaljer
Main Authors: Miller, Michelle M., Iglesias, Diana M., Zhang, Zhao, Corsini, Rachel, Chu, LeeLee, Murawski, Inga, Gupta, Indra, Somlo, Stefan, Germino, Gregory G., Goodyer, Paul R.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879791/
https://ncbi.nlm.nih.gov/pubmed/21389971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2011.56
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