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T-Cell Factor/β-Catenin Activity is Suppressed Normally in Two Independent Models of Autosomal Dominant Polycystic Kidney Disease
During murine kidney development, canonical WNT signalling is highly active in the renal tubules until about embryonic day E16-E18 when β-catenin transcriptional activity becomes progressively restricted to the nephrogenic zone. Several in vitro studies have found a link between cilial signalling an...
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Main Authors: | , , , , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2011
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3879791/ https://ncbi.nlm.nih.gov/pubmed/21389971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2011.56 |
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