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Mutational and Structural Analysis of the Tandem Zinc Finger Domain of Tristetraprolin
Tristetraprolin (TTP), the best known member of a class of tandem (R/K)YKTELCX(8)CX(5)CX(3)H zinc finger proteins, can destabilize target mRNAs by first binding to AU-rich elements (AREs) in their 3′-untranslated regions (UTRs) and subsequently promoting deadenylation and ultimate destruction of tho...
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| Asıl Yazarlar: | , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3879578/ https://ncbi.nlm.nih.gov/pubmed/24253039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.466326 |
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