Tubulation of Endosomal Structures in Human Dendritic Cells by Toll-like Receptor Ligation and Lymphocyte Contact Accompanies Antigen Cross-presentation

Mouse dendritic cells (DCs) can rapidly extend their Class II MHC-positive late endosomal compartments into tubular structures, induced by Toll-like receptor (TLR) triggering. Within antigen-presenting DCs, tubular endosomes polarize toward antigen-specific CD4(+) T cells, which are considered benef...

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Bibliographic Details
Main Authors: Compeer, Ewoud B., Flinsenberg, Thijs W. H., Boon, Louis, Hoekstra, Mirjam E., Boes, Marianne
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879573/
https://ncbi.nlm.nih.gov/pubmed/24235148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.511147
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