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Simulations of Enhancer Evolution Provide Mechanistic Insights into Gene Regulation
There is growing interest in models of regulatory sequence evolution. However, existing models specifically designed for regulatory sequences consider the independent evolution of individual transcription factor (TF)–binding sites, ignoring that the function and evolution of a binding site depends o...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3879441/ https://ncbi.nlm.nih.gov/pubmed/24097306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/mst170 |
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